The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production

The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production

Dengue virus NS5 is the most highly conserved amongst the viral non-structural proteins and is responsible for capping, methylation and replication of the flavivirus RNA genome. Interactions of NS5 with host proteins also modulate host immune responses. Although replication occurs in the cytoplasm,...

Full description

Bibliographic Details
Main Authors: Chan, Kitti W. K., Tay, Moon Y. F., Smith, Kate, Ng, Ivan H. W., Zhao, Yongqian, Ooi, Eng Eong, Lescar, Julien, Luo, Dahai, Jans, David A., Forwood, Jade K., Vasudevan, Subhash G.
Other Authors: Rey, Félix A.
Format: Journal Article
Language:English
Published: 2017
Subjects:
C-terminal 18
Dengue Virus NS5
Online Access:https://hdl.handle.net/10356/83021
http://hdl.handle.net/10220/42375

Internet

https://hdl.handle.net/10356/83021
http://hdl.handle.net/10220/42375

Similar Items