Presence of negative supercoiling in aggregates of histone H1-plasmidic polynucleosome complexes

It was shown in the past that in the presence of histone H1, plasmidic polynucleosomes formed densely packed aggregates. Our current studies demonstrate that these aggregates are susceptible to the actions of E. coli topoisomerase I, human topoisomerase I and DNA nicking enzyme, which is the indicat...

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Bibliographic Details
Main Authors: Zhang, Hao, Li, Tianhu
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2017
Subjects:
Online Access:https://hdl.handle.net/10356/83232
http://hdl.handle.net/10220/42505