The role of macrophages in early phases of type 2 diabetes mellitus
Inflammatory response is a hallmark process of type 2 diabetes mellitus (T2DM) development and progression. In overt hyperglycaemia, low-grade inflammation of the pancreatic islets is known to cause β-cell dysfunction paving way for the pathogenesis of T2DM. Macrophages are vital elements of the imm...
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Format: | Thesis |
Language: | English |
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2018
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Online Access: | https://hdl.handle.net/10356/83668 http://hdl.handle.net/10220/46661 |