Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

Artemisinin resistance in Plasmodium falciparum threatens global efforts to control and eliminate malaria. Polymorphisms in the kelch domain–carrying protein K13 are associated with artemisinin resistance, but the underlying molecular mechanisms are unknown. We analyzed the in vivo transcriptomes of...

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Bibliographic Details
Main Authors: Mok, S., Ashley, E. A., Ferreira, P. E., Zhu, L., Lin, Z., Yeo, T., Chotivanich, K., Imwong, M., Pukrittayakamee, S., Dhorda, M., Nguon, C., Lim, P., Amaratunga, C., Suon, S., Hien, T. T., Htut, Y., Faiz, M. A., Onyamboko, M. A., Mayxay, M., Newton, P. N., Tripura, R., Woodrow, C. J., Miotto, O., Kwiatkowski, D. P., Nosten, F., Day, N. P. J., Preiser, P. R., White, N. J., Dondorp, A. M., Fairhurst, R. M., Bozdech, Z.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2016
Subjects:
Malaria parasites
Online Access:https://hdl.handle.net/10356/83802
http://hdl.handle.net/10220/41453

Internet

https://hdl.handle.net/10356/83802
http://hdl.handle.net/10220/41453

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