Modulating release of ranibizumab and aflibercept from thiolated chitosan-based hydrogels for potential treatment of ocular neovascularization
Background: This paper describes the synthesis of thiolated chitosan-based hydrogels with varying degrees of crosslinking that has been utilized to modulate release kinetics of two clinically relevant FDA-approved anti-VEGF protein drugs, ranibizumab and aflibercept. These hydrogels have been fabric...
Main Authors: | Moreno, Miguel, Pow, Poh Yih, Tan, Su Teng Tabitha, Nirmal, Sonali, Larsson, Andreas, Radhakrishnan, Krishna, Nirmal, Jayabalan, Quah, Soo Tng, Shochat, Susana Geifman, Agrawal, Rupesh, Venkatraman, Subbu S. |
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Other Authors: | School of Materials Science & Engineering |
Format: | Journal Article |
Language: | English |
Published: |
2017
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/84063 http://hdl.handle.net/10220/42956 |
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