Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis

Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis

Sox2 is known to be important for neuron formation, but the precise mechanism through which it activates a neurogenic program and how this differs from its well-established function in self-renewal of stem cells remain elusive. In this study, we identified a highly conserved cyclin-dependent kinase...

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Bibliographic Details
Main Authors: Lim, Shuhui, Bhinge, Akshay, Bragado Alonso, Sara, Aksoy, Irene, Aprea, Julieta, Cheok, Chit Fang, Calegari, Federico, Stanton, Lawrence W., Kaldis, Philipp
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2017
Subjects:
Neural stem cells
Cell cycle regulation
Online Access:https://hdl.handle.net/10356/84199
http://hdl.handle.net/10220/43570

Internet

https://hdl.handle.net/10356/84199
http://hdl.handle.net/10220/43570

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