GapmeR cellular internalization by macropinocytosis induces sequence-specific gene silencing in human primary T-cells

GapmeR cellular internalization by macropinocytosis induces sequence-specific gene silencing in human primary T-cells

Post-transcriptional gene silencing holds great promise in discovery research for addressing intricate biological questions and as therapeutics. While various gene silencing approaches, such as siRNA and CRISPR-Cas9 techniques, are available, these cannot be effectively applied to “hard-to-transfect...

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Bibliographic Details
Main Authors: Fazil, Mobashar Hussain Urf Turabe, Ong, Seow Theng, Chalasani, Madhavi Latha Somaraju, Low, Jian Hui, Kizhakeyil, Atish, Mamidi, Akshay, Lim, Carey Fang Hui, Wright, Graham D., Lakshminarayanan, Rajamani, Kelleher, Dermot, Verma, Navin Kumar
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2016
Subjects:
T cells
Translational immunology
Online Access:https://hdl.handle.net/10356/84347
http://hdl.handle.net/10220/41790

Internet

https://hdl.handle.net/10356/84347
http://hdl.handle.net/10220/41790

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