Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection

Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection

The recent discovery of small molecules targeting the cytochrome bc 1 : aa 3 in Mycobacterium tuberculosis triggered interest in the terminal respiratory oxidases for antituberculosis drug development. The mycobacterial cytochrome bc 1 : aa 3 consists of a menaquinone:cytochrome c reductase ( bc 1 )...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkkit: Hasenoehrl, Erik J., Koh, Vanessa H., Ang, Michelle L. T., Sajorda, Dannah R., Hards, Kiel, Grüber, Gerhard, Alonso, Sylvie, Cook, Gregory M., Berney, Michael, Pethe, Kevin, Kalia, Nitin Pal, Ab Rahman, Nurlilah Binte
Eará dahkkit: Lee Kong Chian School of Medicine (LKCMedicine)
Materiálatiipa: Journal Article
Giella:English
Almmustuhtton: 2017
Fáttát:
Bioenergetics
Oxidative Phosphorylation
Liŋkkat:https://hdl.handle.net/10356/84353
http://hdl.handle.net/10220/43577

Interneahtta

https://hdl.handle.net/10356/84353
http://hdl.handle.net/10220/43577

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