A supersaturating delivery system of silibinin exhibiting high payload achieved by amorphous nano-complexation with chitosan
The therapeutic potentials of silibinin – a phytochemical isolated from milk thistle plants – have not been fully realized due to its poor oral bioavailability caused by the low aqueous solubility. Existing solubility enhancement strategies of silibinin by nanonization were limited by their low payl...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/84608 http://hdl.handle.net/10220/41896 |