Water-Bridge Mediates Recognition of mRNA Cap in eIF4E

Water-Bridge Mediates Recognition of mRNA Cap in eIF4E

Ligand binding pockets in proteins contain water molecules, which play important roles in modulating protein-ligand interactions. Available crystallographic data for the 5′ mRNA cap-binding pocket of the translation initiation factor protein eIF4E shows several structurally conserved waters, which a...

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Bibliographic Details
Main Authors: Lama, Dilraj, Pradhan, Mohan R., Brown, Christopher J., Eapen, Rohan S., Joseph, Thomas L., Kwoh, Chee-Keong, Lane, David P., Verma, Chandra Shekhar
Other Authors: School of Computer Science and Engineering
Format: Journal Article
Language:English
Published: 2017
Subjects:
Translation initiation factor 4E protein
5′ mRNA cap
Online Access:https://hdl.handle.net/10356/84992
http://hdl.handle.net/10220/42071

Internet

https://hdl.handle.net/10356/84992
http://hdl.handle.net/10220/42071

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