Interaction Analyses of the Integrin β2 Cytoplasmic Tail with the F3 FERM Domain of Talin and 14-3-3ζ Reveal a Ternary Complex with Phosphorylated Tail

Integrins, which are heterodimeric (α and β subunits) signal-transducer proteins, are essential for cell adhesion and migration. β cytosolic tails (β-CTs) of integrins interact with a number of cytosolic proteins including talin, Dok1, and 14-3-3ζ. The formation of multiprotein complexes with β-CTs...

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Bibliographic Details
Main Authors: Chatterjee, Deepak, Lu, Lewis Zhiping, Tan, Suet-Mien, Bhattacharjya, Surajit
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2017
Subjects:
Online Access:https://hdl.handle.net/10356/85152
http://hdl.handle.net/10220/43654