Electron microscopy and biochemical analysis of native telomeric chromatin
Human telomeres are G-rich sequence repeats of DNA that span the terminal ends of chromosomes with an average length of about 10,000 base pairs. Telomeric DNA acts as a platform for the recruitment of a six protein-complex called shelterin. The shelterin complex protects chromosome ends from fusion...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2019
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| Online Access: | https://hdl.handle.net/10356/85247 http://hdl.handle.net/10220/49204 |