Dengue virus-infected dendritic cells, but not monocytes, activate natural killer cells through a contact-dependent mechanism involving adhesion molecules

Dengue virus-infected dendritic cells, but not monocytes, activate natural killer cells through a contact-dependent mechanism involving adhesion molecules

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Natural killer (NK) cells play a protective role against dengue virus (DENV) infection, but the cellular and molecular mechanisms are not fully understood. Using an optimized humanized mouse model, we show that human NK cells, through the secretion of gamma interferon (IFN-γ), are critical in the ea...

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Bibliografski detalji
Glavni autori: Costa, Vivian Vasconcelos, Ye, Weijian, Chen, Qingfeng, Teixeira, Mauro Martins, Preiser, Peter, Ooi, Eng Eong, Chen, Jianzhu
Daljnji autori: Palese, Peter
Format: Journal Article
Jezik:English
Izdano: 2019
Teme:
Dengue Virus
Adhesion Molecule
Science::Biological sciences
Online pristup:https://hdl.handle.net/10356/85405
http://hdl.handle.net/10220/50195

Internet

https://hdl.handle.net/10356/85405
http://hdl.handle.net/10220/50195

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