Ezh2 controls skin tolerance through distinct mechanisms in different subsets of skin dendritic cells

Ezh2 controls skin tolerance through distinct mechanisms in different subsets of skin dendritic cells

Ezh2, a well-established epigenetic repressor, can down-regulate leukocyte inflammatory responses, but its role in cutaneous health remains elusive. Here we demonstrate that Ezh2 controls cutaneous tolerance by regulating Langerhans cell (LC) transmigration across the epidermal basement membrane dir...

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Bibliographic Details
Main Authors: Morita, Akimichi, Ginhoux, Florent, Loh, Jia Tong, Lim, Thomas Jun Feng, Ikumi, Kyoko, Matoba, Takuma, Janela, Baptiste, Gunawan, Merry, Toyama, Tatsuya, Bunjamin, Maegan, Ng, Lai Guan, Poidinger, Michael, Yamazaki, Sayuri, Lam, Kong-Peng, Su, I-hsin
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2019
Subjects:
Dermatology
Immunology
Science::Biological sciences
Online Access:https://hdl.handle.net/10356/85704
http://hdl.handle.net/10220/49842

Internet

https://hdl.handle.net/10356/85704
http://hdl.handle.net/10220/49842

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