Porcine hepatocytes culture on biofunctionalized 3D inverted colloidal crystal scaffolds as an in vitro model for predicting drug hepatotoxicity

As drug-induced hepatotoxicity represents one of the most common causes of drug failure, three-dimensional (3D) in vitro liver platforms represent a fantastic toolbox to predict drug toxicity and thus reduce in vivo animal studies and lessen drug attrition rates. The aim of this study is to establis...

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Bibliographic Details
Main Authors: Wu, Lingyan, Ferracci, Gaia, Wang, Yan, Fan, Teng Fei, Cho, Nam-Joon, Chow, Pierce K. H.
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/85716
http://hdl.handle.net/10220/49833