A ferritin-containing nanoconjugate as MRI image-guidance to target Necl-5, a tumor-surface antigen: a potential thermal accelerant for microwave ablation

Purpose: A ferritin-containing nanoparticle conjugated with a target-specific antibody was investigated as a MRI contrast agent for tumor detection. A genetically modified ferritin to markedly improve Fe (III) payload (up to 7,000 Fe ions), was chemically tethered to a monoclonal antibody against ra...

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Bibliographic Details
Main Authors: Park, William K. C., Mills, David R., Lim, Sierin, Sana, Barindra, Frank, Victoria E., Kenyon, Brendan M., Primmer, Michael P., Paul, Jarod B., Baird, Greyson L., Walsh, Edward G., Dupuy, Damian E.
Other Authors: Ryan, Thomas P.
Format: Conference Paper
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/86825
http://hdl.handle.net/10220/44303