Allosteric cross-talk in chromatin can mediate drug-drug synergy

Exploitation of drug–drug synergism and allostery could yield superior therapies by capitalizing on the immensely diverse, but highly specific, potential associated with the biological macromolecular landscape. Here we describe a drug–drug synergy mediated by allosteric cross-talk in chromatin, wher...

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Bibliografske podrobnosti
Main Authors: Adhireksan, Zenita, Palermo, Giulia, Riedel, Tina, Ma, Zhujun, Muhammad, Reyhan, Rothlisberger, Ursula, Dyson, Paul J., Davey, Curtis Alexander
Drugi avtorji: School of Biological Sciences
Format: Journal Article
Jezik:English
Izdano: 2018
Teme:
Online dostop:https://hdl.handle.net/10356/87027
http://hdl.handle.net/10220/44277