Heterochromatin protein 1a functions for piRNA biogenesis predominantly from pericentric and telomeric regions in Drosophila

In metazoan germline, Piwi-interacting RNAs (piRNAs) provide defence against transposons. Piwi–piRNA complex mediates transcriptional silencing of transposons in nucleus. Heterochromatin protein 1a (HP1a) has been proposed to function downstream of Piwi-piRNA complex in Drosophila. Here we show that...

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Bibliographic Details
Main Authors: Teo, Ryan Yee Wei, Anand, Amit, Sridhar, Vishweshwaren, Okamura, Katsutomo, Kai, Toshie
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87041
http://hdl.handle.net/10220/45294