Essential role of the flexible linker on the conformational equilibrium of bacterial peroxiredoxin reductase for effective regeneration of peroxiredoxin

Reactive oxygen species (ROS) can damage DNA, proteins, and lipids, so cells have antioxidant systems that regulate ROS. In many bacteria, a dedicated peroxiredoxin reductase, alkyl hydroperoxide reductase subunit F (AhpF), catalyzes the rapid reduction of the redox-active disulfide center of the an...

Description complète

Détails bibliographiques
Auteurs principaux: Grüber, Gerhard, Kamariah, Neelagandan, Eisenhaber, Birgit, Eisenhaber, Frank
Autres auteurs: School of Computer Science and Engineering
Format: Journal Article
Langue:English
Publié: 2018
Sujets:
Accès en ligne:https://hdl.handle.net/10356/87081
http://hdl.handle.net/10220/44312