EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms

Recently, we reported that the histone methyltransferase, EZH2, controls leukocyte migration through interaction with the cytoskeleton remodeling effector, VAV, and direct methylation of the cytoskeletal regulatory protein, Talin. However, it is unclear whether this extranuclear, epigenetic-independ...

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Bibliographic Details
Main Authors: Venkatesan, Nandini, Wong, Jong Fu, Tan, Kuan Pern, Chung, Hwa Hwa, Yau, Yin Hoe, Cukuroglu, Engin, Allahverdi, Abdollah, Nordenskiold, Lars, Goke, Jonathan, Geifman-Shochat, Susana, Lin, Valerie Chun Ling, Madhusudhan, M. S., Su, I-hsin
Other Authors: School of Computer Science and Engineering
Format: Journal Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87507
http://hdl.handle.net/10220/44455