Nicotinamide metabolism modulates the proliferation/differentiation balance and senescence of human primary keratinocytes

Nicotinamide metabolism modulates the proliferation/differentiation balance and senescence of human primary keratinocytes

Nicotinamide (NAM) is the main precursor of nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for DNA repair, glycolysis, and oxidative phosphorylation. NAM has anti-aging activity on human skin, but the underlying mechanisms of action are unclear. Using 3-dimensional organotypic skin m...

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Bibliographic Details
Main Authors: Tan, Chye Ling, Chin, Toby, Tan, Christina Yan Ru, Rovito, Holly A., Quek, Ling Shih, Oblong, John E., Bellanger, Sophie
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2019
Subjects:
HPK (Human Primary Keratinocyte)
ATP (Adenosine Triphosphate)
Science::Biological sciences
Online Access:https://hdl.handle.net/10356/87642
http://hdl.handle.net/10220/49890

Internet

https://hdl.handle.net/10356/87642
http://hdl.handle.net/10220/49890

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