Structural and functional characterization of flavivirus non-structural protein 3 (NS3) in solution and atomic and enzymatic insights of vancomysin resistant enterococcus faecalis (V583) alkyl hydroperoxide subunit C
This thesis focuses on the non-structural protein 3 (NS3) of two flaviviral pathogens, the Dengue (DENV; DENV-2) and Zika virus (ZIKV), that have emerged as a major health concern in Singapore and world-wide. The NS3 comprises of an N-terminal serine protease domain and a C-terminal helicase domain...
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| Format: | Thesis |
| Language: | English |
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2018
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| Online Access: | https://hdl.handle.net/10356/87918 http://hdl.handle.net/10220/45578 |