From the unfolded protein response to metabolic diseases – lipids under the spotlight
The unfolded protein response (UPR) is classically viewed as a stress response pathway to maintain protein homeostasis at the endoplasmic reticulum (ER). However, it has recently emerged that the UPR can be directly activated by lipid perturbation, independently of misfolded proteins. Comprising pri...
Main Authors: | , , |
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Other Authors: | |
Format: | Journal Article |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/87971 http://hdl.handle.net/10220/45592 |