Development of a multi-compartment population balance model for high-shear wet granulation with discrete element method

This paper presents a multi-compartment population balance model for wet granulation coupled with DEM (discrete element method) simulations. Methodologies are developed to extract relevant data from the DEM simulations to inform the population balance model. First, compartmental residence times are...

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Bibliographic Details
Main Authors: Lee, Kok Foong, Dosta, Maksym, McGuire, Andrew D., Mosbach, Sebastian, Wagner, Wolfgang, Heinrich, Stefan, Kraft, Markus
Other Authors: School of Chemical and Biomedical Engineering
Format: Journal Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/88020
http://hdl.handle.net/10220/44503