Charged residues next to transmembrane regions revisited: “Positive-inside rule” is complemented by the “negative inside depletion/outside enrichment rule”

Background: Transmembrane helices (TMHs) frequently occur amongst protein architectures as means for proteins to attach to or embed into biological membranes. Physical constraints such as the membrane’s hydrophobicity and electrostatic potential apply uniform requirements to TMHs and their flanking...

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Bibliografische gegevens
Hoofdauteurs: Baker, James Alexander, Wong, Wing-Cheong, Eisenhaber, Birgit, Warwicker, Jim, Eisenhaber, Frank
Andere auteurs: School of Computer Science and Engineering
Formaat: Journal Article
Taal:English
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://hdl.handle.net/10356/88052
http://hdl.handle.net/10220/44533