Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches
The Hippo signaling pathway, which is implicated in the regulation of organ size, has emerged as a potential target for the development of cancer therapeutics. YAP, TAZ (transcription co-activators) and TEAD (transcription factor) are the downstream transcriptional machinery and effectors of the pat...
| Main Authors: | , , , , |
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| מחברים אחרים: | |
| פורמט: | Journal Article |
| שפה: | English |
| יצא לאור: |
2018
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| נושאים: | |
| גישה מקוונת: | https://hdl.handle.net/10356/88193 http://hdl.handle.net/10220/44583 |