Conservative site-specific and single-copy transgenesis in human LINE-1 elements
Genome engineering of human cells plays an important role in biotechnology and molecular medicine. In particular, insertions of functional multi-transgene cassettes into suitable endogenous sequences will lead to novel applications. Although several tools have been exploited in this context, safety...
Main Authors: | , , , , , , , , , , , |
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其他作者: | |
格式: | Journal Article |
语言: | English |
出版: |
2018
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主题: | |
在线阅读: | https://hdl.handle.net/10356/88523 http://hdl.handle.net/10220/45846 |