Proinflammatory cytokines induce endocrine differentiation in pancreatic ductal cells via STAT3-dependent NGN3 activation

A major goal of diabetes research is to develop strategies that replenish pancreatic insulin-producing beta cells. One emerging strategy is to harness pancreatic plasticity—the ability of pancreatic cells to undergo cellular interconversions—a phenomenon implicated in physiological stress and pancre...

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Bibliographic Details
Main Authors: Valdez, Ivan Achel, Dirice, Ercument, Gupta, Manoj K., Shirakawa, Jun, Teo, Adrian Kee Keong, Kulkarni, Rohit N.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/88611
http://hdl.handle.net/10220/46945