Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant Enterococci (VRE) in Vitro and in Vivo
The cyclic depsipeptide, teixobactin, kills a number of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), and Mycobacterium tuberculosis without detectable resistance. To date, teixobactin is the only molecule in its class that has shown in vivo antibacterial effi...
Main Authors: | Parmar, Anish, Lakshminarayanan, Rajamani, Iyer, Abhishek, Mayandi, Venkatesh, Goh, Eunice Tze Leng, Lloyd, Daniel G., Chalasani, Madhavi Latha Somaraju, Verma, Navin Kumar, Prior, Stephen H., Beuerman, Roger W., Madder, Annemieke, Taylor, Edward J., Singh, Ishwar |
---|---|
Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Journal Article |
Language: | English |
Published: |
2018
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/88754 http://hdl.handle.net/10220/44693 |
Similar Items
-
Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA)
by: Ruba Malkawi, et al.
Published: (2018-10-01) -
Investigation of the N-Terminus Amino Function of Arg10-Teixobactin
by: Shimaa A. H. Abdel Monaim, et al.
Published: (2017-09-01) -
Antimicrobial Effects of <i><sub>L</sub></i>-Chg<sub>10</sub>-Teixobactin against <i>Enterococcus faecalis</i> In Vitro
by: Alaa Jarkhi, et al.
Published: (2022-05-01) -
Antibiotic resistance of enterococci, coagulase negative staphylococci and Staphylococcus aureus isolated from chicken meat
by: Naci Erhan Yurdakul, et al.
Published: (2013-02-01) -
Vancomycin resistant enterococci (VRE) in Swedish sewage sludge
by: Aspan Anna, et al.
Published: (2009-05-01)