How RNA catalyzes cyclization

The long-awaited crystal structure of the Varkud satellite (VS) ribozyme dimer provides atomic-level insights into how the VS ribozyme folds and catalyzes RNA circularization during rolling circle replication, as well as revealing convergent evolution used by RNAs to catalyze an SN2 reaction.

Bibliographic Details
Main Authors: Zhong, Zhensheng, Chen, Gang
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/89213
http://hdl.handle.net/10220/44839