Development of novel agonists for the orphan nuclear receptor, Nurr1 : a therapeutic strategy for Parkinson’s disease
Parkinson’s Disease (PD) is the second most prevalent neurodegenerative disease among the elderly. It is characterized pathologically by the demise of dopaminergic (DA) neurons in the substantia nigra region of the midbrain resulting in the loss of motor function. The orphan nuclear receptor, Nurr1,...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2019
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| Online Access: | https://hdl.handle.net/10356/89266 http://hdl.handle.net/10220/48045 |