Aza-bridged bisphenanthrolinyl Pt(ii) complexes : efficient stabilization and topological selectivity on telomeric G-quadruplexes

Two platinum complexes with an aza-bridged bis(1,10-phenanthrolin-2-yl)amine (bpa) were synthesized. The two phenanthrolines in bpa entered a flat plane prior to binding of nucleic acids, which bestowed on the two Pt complexes a significantly high stabilizing ability on both DNA and RNA G-quadruplex...

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Détails bibliographiques
Auteurs principaux: He, Lei, Meng, Zhenyu, Xie, Yi-qun, Chen, Xiang, Li, Tianhu, Shao, Fangwei
Autres auteurs: School of Physical and Mathematical Sciences
Format: Journal Article
Langue:English
Publié: 2018
Sujets:
Accès en ligne:https://hdl.handle.net/10356/89489
http://hdl.handle.net/10220/44940