Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework

Cancer cells undergoing epithelial-mesenchymal transition (EMT) acquire stem cell-like phenotype associated with malignant behaviour, chemoresistance, and relapse. Current two-dimensional (2D) in-vitro culture models of tumorigenesis are inadequate to replicate the complexity of in-vivo microenviron...

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Dettagli Bibliografici
Autori principali: Pal, Mintu, Chen, Huizhi, Lee, Bae Hoon, Lee, Justin Yin Hao, Yip, Yun Sheng, Tan, Nguan Soon, Tan, Lay Poh
Altri autori: School of Materials Science & Engineering
Natura: Journal Article
Lingua:English
Pubblicazione: 2019
Soggetti:
Accesso online:https://hdl.handle.net/10356/89858
http://hdl.handle.net/10220/49325