Neighborhood regularized logistic matrix factorization for drug-target interaction prediction

In pharmaceutical sciences, a crucial step of the drug discovery process is the identification of drug-target interactions. However, only a small portion of the drug-target interactions have been experimentally validated, as the experimental validation is laborious and costly. To improve the drug di...

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Bibliographic Details
Main Authors: Liu, Yong, Wu, Min, Miao, Chunyan, Zhao, Peilin, Li, Xiao-Li
Other Authors: Przytycka, Teresa M.
Format: Journal Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/89929
http://hdl.handle.net/10220/46442