Enantioselective oxidative cross-dehydrogenative coupling of tertiary amines to aldehydes
An enantioselective and direct oxidative coupling of aldehydes to tertiary amines to give β-amino alcohols is described. Catalyzed by copper(II), the reaction proceeds to give a racemic mixture of products; however, by using a combination of copper(II) and a chiral amine catalyst, the reaction gives...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/94637 http://hdl.handle.net/10220/8116 |
| _version_ | 1826122366290231296 |
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| author | Zhang, Junmin Tiwari, Bhoopendra Xing, Chong Chen, Xingkuan Chi, Robin Yonggui |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Zhang, Junmin Tiwari, Bhoopendra Xing, Chong Chen, Xingkuan Chi, Robin Yonggui |
| author_sort | Zhang, Junmin |
| collection | NTU |
| description | An enantioselective and direct oxidative coupling of aldehydes to tertiary amines to give β-amino alcohols is described. Catalyzed by copper(II), the reaction proceeds to give a racemic mixture of products; however, by using a combination of copper(II) and a chiral amine catalyst, the reaction gives the desired products with high enantioselectivity. |
| first_indexed | 2024-10-01T05:47:19Z |
| format | Journal Article |
| id | ntu-10356/94637 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:47:19Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | ntu-10356/946372020-03-07T12:31:30Z Enantioselective oxidative cross-dehydrogenative coupling of tertiary amines to aldehydes Zhang, Junmin Tiwari, Bhoopendra Xing, Chong Chen, Xingkuan Chi, Robin Yonggui School of Physical and Mathematical Sciences DRNTU::Science::Mathematics::Applied mathematics An enantioselective and direct oxidative coupling of aldehydes to tertiary amines to give β-amino alcohols is described. Catalyzed by copper(II), the reaction proceeds to give a racemic mixture of products; however, by using a combination of copper(II) and a chiral amine catalyst, the reaction gives the desired products with high enantioselectivity. 2012-05-22T08:43:27Z 2019-12-06T18:59:33Z 2012-05-22T08:43:27Z 2019-12-06T18:59:33Z 2012 2012 Journal Article Zhang, J., Tiwari, B., Xing, C., Chen, X. & Chi, R. Y. (2012). Enantioselective Oxidative Cross-Dehydrogenative Coupling of Tertiary Amines to Aldehydes. Angewandte Chemie International Edition, 51(15), 3649-3652. https://hdl.handle.net/10356/94637 http://hdl.handle.net/10220/8116 10.1002/anie.201109054 165019 en Angewandte chemie international edition © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| spellingShingle | DRNTU::Science::Mathematics::Applied mathematics Zhang, Junmin Tiwari, Bhoopendra Xing, Chong Chen, Xingkuan Chi, Robin Yonggui Enantioselective oxidative cross-dehydrogenative coupling of tertiary amines to aldehydes |
| title | Enantioselective oxidative cross-dehydrogenative coupling of tertiary amines to aldehydes |
| title_full | Enantioselective oxidative cross-dehydrogenative coupling of tertiary amines to aldehydes |
| title_fullStr | Enantioselective oxidative cross-dehydrogenative coupling of tertiary amines to aldehydes |
| title_full_unstemmed | Enantioselective oxidative cross-dehydrogenative coupling of tertiary amines to aldehydes |
| title_short | Enantioselective oxidative cross-dehydrogenative coupling of tertiary amines to aldehydes |
| title_sort | enantioselective oxidative cross dehydrogenative coupling of tertiary amines to aldehydes |
| topic | DRNTU::Science::Mathematics::Applied mathematics |
| url | https://hdl.handle.net/10356/94637 http://hdl.handle.net/10220/8116 |
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