Intrinsic differences between authentic and cryptic 5' splice sites

Cryptic splice sites are used only when use of a natural splice site is disrupted by mutation. To determine the features that distinguish authentic from cryptic 5′ splice sites (5′ss), we systematically analyzed a set of 76 cryptic 5′ss derived from 46 human genes. These cryptic 5′ss have a similar...

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Bibliographic Details
Main Authors: Krainer, Adrian R., Sachidanandam, Ravi, Roca, Xavier
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/95535
http://hdl.handle.net/10220/8876