Catalytic enantioselective conjugate addition of grignard reagents to cyclic enones using C 1 -1,1′-bisisoquinoline-based chiral ligands
New highly constrained chiral C1-1,10-bisisoquinoline ligands were examined in the enantioselective conjugate addition of Grignard reagents to cyclohexenone and cyclopentenone. The desired 1,4-adducts were obtained in excellent yield and moderate enantiomeric excess (up to 35%).
| Những tác giả chính: | , |
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| Tác giả khác: | |
| Định dạng: | Journal Article |
| Ngôn ngữ: | English |
| Được phát hành: |
2013
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| Truy cập trực tuyến: | https://hdl.handle.net/10356/96144 http://hdl.handle.net/10220/11770 |