Substrate channel flexibility in Pseudomonas aeruginosa MurB accommodates two distinct substrates

Biosynthesis of UDP-N-acetylmuramic acid in bacteria is a committed step towards peptidoglycan production. In an NADPH- and FAD-dependent reaction, the UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) reduces UDP-N-acetylglucosamine-enolpyruvate to UDP-N-acetylmuramic acid. We determined the th...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Chen, Ming Wei, Lohkamp, Bernhard, Schnell, Robert, Lescar, Julien, Schneider, Gunter
Awduron Eraill: School of Biological Sciences
Fformat: Journal Article
Iaith:English
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://hdl.handle.net/10356/96311
http://hdl.handle.net/10220/11918