Substrate channel flexibility in Pseudomonas aeruginosa MurB accommodates two distinct substrates
Biosynthesis of UDP-N-acetylmuramic acid in bacteria is a committed step towards peptidoglycan production. In an NADPH- and FAD-dependent reaction, the UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) reduces UDP-N-acetylglucosamine-enolpyruvate to UDP-N-acetylmuramic acid. We determined the th...
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Fformat: | Journal Article |
Iaith: | English |
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2013
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Mynediad Ar-lein: | https://hdl.handle.net/10356/96311 http://hdl.handle.net/10220/11918 |