STEROID : in silico heuristic target combination identification for disease-related signaling networks

Given a signaling network, the target combination identification problem aims to predict efficacious and safe target combinations for treatment of a disease. State-of-the-art in silico methods use Monte Carlo simulated annealing (mcsa) to modify a candidate solution stochastically, and use the Metro...

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Bibliographic Details
Main Authors: Bhowmick, Sourav S., Chua, Huey-Eng, Tucker-Kellogg, Lisa, Dewey Jr., C. Forbes
Other Authors: School of Computer Engineering
Format: Conference Paper
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/96343
http://hdl.handle.net/10220/11924