RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage

RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage

RNA-binding protein HuR modulates the stability and translational efficiency of messenger RNAs (mRNAs) encoding essential components of the cellular proliferation, growth and survival pathways. Consistent with these functions, HuR levels are often elevated in cancer cells and reduced in senescent an...

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Bibliographic Details
Main Authors: Dai, Weijun, Zhang, Gen, Makeyev, Eugene V.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2013
Subjects:
DRNTU::Science::Biological sciences
DRNTU::Science::Biological sciences::Human anatomy and physiology::Deoxyribonucleic acids
Online Access:https://hdl.handle.net/10356/96896
http://hdl.handle.net/10220/10011

Internet

https://hdl.handle.net/10356/96896
http://hdl.handle.net/10220/10011

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