Palladium-catalyzed, asymmetric Mizoroki–Heck reaction of benzylic electrophiles using phosphoramidites as chiral ligands
We report herein the first examples of asymmetric Mizoroki–Heck reactions using benzyl electrophiles. A new phosphoramidite was identified to be an effective chiral ligand in the palladium–catalyzed reaction. The reaction is compatible with polar functional groups and can be readily scaled up. Sever...
Main Authors: | , |
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Other Authors: | |
Format: | Journal Article |
Language: | English |
Published: |
2013
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Online Access: | https://hdl.handle.net/10356/97595 http://hdl.handle.net/10220/11228 |