Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice

Aims/hypothesis Although myostatin-null (Mstn −/−) mice fail to accumulate fat in adipose tissue when fed a high-fat diet (HFD), little is known about the molecular mechanism(s) behind this phenomenon. We therefore sought to identify the signalling pathways through which myostatin regulates accumul...

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Bibliographic Details
Main Authors: Gluckman, Peter D., Zhang, C., Masuda, S., Kambadur, R., McFarlane, Craig, Lokireddy, Sudarsanareddy, Ge, Xiaojia, Sharma, Mridula
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/97641
http://hdl.handle.net/10220/13216