Structural basis for promiscuity and specificity during Candida glabrata invasion of host epithelia

The human pathogenic yeast Candida glabrata harbors more than 20 surface-exposed, epithelial adhesins (Epas) for host cell adhesion. The Epa family recognizes host glycans and discriminates between target tissues by their adhesin (A) domains, but a detailed structural basis for ligand-binding specif...

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Bibliographic Details
Main Authors: Maestre-Reyna, M., Diderrich, R., Veelders, M. S., Eulenburg, G., Kalugin, V., Brückner, S., Keller, P., Rupp, S., Mösch, H.-U., Essen, L.-O.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/97909
http://hdl.handle.net/10220/12333