Cephalosporin-3′-diazeniumdiolates : targeted NO-donor prodrugs for dispersing bacterial biofilms
Just say NO to biofilms: NO-donors are used to disperse a bacterial biofilm so that co-administered antibiotics will kill the more susceptible unattached cells. The chemically stable cephalosporin-3′-diazeniumdiolate NO-donor prodrug (see scheme) is activated by bacterial β-lactamases and facilitate...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/98472 http://hdl.handle.net/10220/12454 |