The crystal structure of the Sox4 HMG domain–DNA complex suggests a mechanism for positional interdependence in DNA recognition

It has recently been proposed that the sequence preferences of DNA-binding TFs (transcription factors) can be well described by models that include the positional interdependence of the nucleotides of the target sites. Such binding models allow for multiple motifs to be invoked, such as principal an...

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Bibliographic Details
Main Authors: Jauch, Ralf, Ng, Calista K. L., Narasimhan, Kamesh, Kolatkar, Prasanna R.
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/98725
http://hdl.handle.net/10220/12683