Hematologically important mutations : leukocyte adhesion deficiency (first update)

Leukocyte adhesion deficiency (LAD) is an immunodeficiency caused by defects in the adhesion of leukocytes (especially neutrophils) to the blood vessel wall. As a result, patients with LAD suffer from severe bacterial infections and impaired wound healing, accompanied by neutrophilia. In LAD-I, muta...

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Bibliographic Details
Main Authors: Holland, Steven M., Belohradsky, Bernd H., Kuijpers, Taco W., Van de Vijver, Edith, Maddalena, Anne, Sanal, Özden, Uzel, Gulbu, Madkaikar, Manisha, de Boer, Martin, Van Leeuwen, Karin, Köker, M. Yavuz, Parvaneh, Nima, Fischer, Alain, Law, S. K. Alex, Klein, Nigel, Tezcan, F. Ilhan, Unal, Ekrem, Patiroglu, Turkan, Schwartz, Klaus, Somech, Raz, Roos, Dirk
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/99059
http://hdl.handle.net/10220/12687