OPTIMASI FORMULA TABLET FLOATING - GASTRORETENTIVE NIFEDIPIN MENGGUNAKAN METODE EFFERVESCENT DENGAN MATRIKS HPMC K100M DAN ETILSELULOSA
Nifedipine is a cardiovascular drug with multiple use frequency within one day for a long period of treatment. The absorption of nifedipine in gastric which reaches 90% (Harjono, 2000) but has low dissolution which can cause the decrease of bioavailability. Gastroretentive drug delivery system (GDDS...
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Format: | Thesis |
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[Yogyakarta] : Universitas Gadjah Mada
2013
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