In vitro inhibitory effect of Rubraxanthone isolated from Garcinia psrvifolia on platelet- Activating factor receptor binding

Rubraxanthone and isocowanol isolated from Garcinia parvifolia Miq. were investigated for their inhibitory effects on platelet-activating factor (PAF) binding to rabbit platelets using 3H-PAF as a ligand. Rubraxanthone showed a strong inhibition with IC 50 value of 18.2 microM. The IC 50 values of m...

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Bibliographic Details
Main Authors: Jantan, Ibrahim, Md Pisar, Mazura, Idris, Muhammad Sum, Bakhtiar, M. Taher, Mat Ali, Rasadah
Format: Article
Language:English
Published: Thieme Verlagsgruppe 2002
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Online Access:http://irep.iium.edu.my/12052/1/Plantamedica.pdf