| Summary: | Background: Commercial lidocain preparation are made from HCl solution that
makes it become high acidity. Infiltration injection of lidocain HCl may cause
painful and burning sensation in the injection area. Alkalinization of lidocain HCl
solution with sodium bicarbonate (NaHCO3) may reduce the incidence while
doing intradermal infiltration.
Objectives : To compare incidence of pain between lidocain HCl 2% plus sodium
bicarbonate (NaHCO3) than lidocain HCl 1,8%, infiltrated subcutaneously at
lumbal area.
Methods: 84 male and female adult patient, with a ASA physical status I-II
underwent surgery with local anesthetic infiltration in the lumbar area, injected
before spinal and epidural technique in a randomized controlled trial. Patients will
be randomly divided into two groups A and B which each group will receive a
lidocaine HCl 2% plus NaHCO3 8,4% 0,2 cc (2,2 cc) and lidocaine HCl 1,8% (2,2
cc). Every patient will receive the same subcutaneous infiltration. Pain will be
assessed for 30 minutes after subcutaneous infiltration. Visual Analog Scale
(VAS) as an indicator to assess pain.
Result : Additional of sodium bicarbonate (NaHCO3) 8,4% in lidocain HCl 2%
generate an average pain VAS score in group A (1,48 ± 1,13) compared with
group B that is given a lidocaine 1,8% resulting a VAS score (2,90 ± 1,650).
There is a significant difference (p<0,005) between both groups. The result shows
that group receiving lidocaine HCl 2% plus NaHCO3 8,4% 0,2 cc is more
effective in reducing the pain of infiltration compared with group receiving
lidocaine HCl 1,8%. As details, VAS score in Group A, 7 patient (16,7%) with no
pain, 33 patient (78,6%) with a mild pain, and 2 patient (4,8%) having a moderate
pain response. Meanwhile, in group B patient receiving lidocaine 1,8% showing
variety VAS score that is 3 patient (7,1%) have no pain response, 23 patient
(54,8%) with a mild pain and 15 patient (35,7%) with a moderate pain responds
and 1 patient (2,4%) having severe pain. Average pain response for group A is in
scale 0-4 while in group B is in 0-8.
Conclution : Additional of Sodium bicarbonate (NaHCO3) 8,4% in lidocaine HCl
2%, is more effective in reducing pain after infiltration compared with lidocain
HCl 1,8%
|
|---|