Siklosporin mengubah farmakokenetik sulfametizol pada tikus
ABSTRACT This work aims to study the pharmacokinetics of sulfamethizole in rats pre-treated with cyclosporin, and to seek correlations between total clearance (CL/F) and T1/2 elimination of the drug with creatinine clearance (CLcr,). Female Wistar rats were each injected with the sulfamethizole (40...
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| Formato: | Artigo |
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[Yogyakarta] : Universitas Gadjah Mada
1993
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| Summary: | ABSTRACT
This work aims to study the pharmacokinetics of sulfamethizole in rats pre-treated with cyclosporin, and to seek correlations between total clearance (CL/F) and T1/2 elimination of the drug with creatinine clearance (CLcr,). Female Wistar rats were each injected with the sulfamethizole (40 mg/kg |
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